ydiG [2017-8-11 16:0:3]

molybdenum cofactor biosynthesis protein

locus: BSU05960

pI: 6.22

mw: 18.31 kDa

protein length: 170 aa

gene length: 510 bp

function: unknown

product: molybdenum cofactor biosynthesis protein

essential: no

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.10|Biosynthesis of molybdopterin]

Gene

Coordinates: 646,582 → 647,094

The protein

Catalyzed reaction/ biological activity

• involved in the first step of molybdenum cofactor biosynthesis (together with [protein|19EB8E7CBC0E8D7A6429ADFFF93D1F71EFE3FF11|MoaA])

Protein family

• moaC family (according to Swiss-Prot)

Structure

• [PDB|1EKR] (the protein from ''E. coli'', 51% identity, 78% similarity) [Pubmed|10903949]

Expression and Regulation

Operons

• genes: [gene|4A8D74B83E20FA138ED66F0D8FD456B69B740D92|ydiG]-[gene|B5EF521437323EF43F08E5EFDB5C798616CA499A|rex]-[gene|780FDF3DD260287428B397FFE7F44DDF1917381C|tatAY]-[gene|E60FC9C9B273DD6B07B7B95819525DE5F35113CE|tatCY]
  description: [Pubmed|22383849]

  regulation

  • constitutitvely expressed [Pubmed|22383849]
  • the mRNA is processed between [gene|B5EF521437323EF43F08E5EFDB5C798616CA499A|rex] and [gene|780FDF3DD260287428B397FFE7F44DDF1917381C|tatAY] by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y], this requires the [protein|EE52DFA35B935E551871D079A9BE877DB2001A3B|YmcA]-[protein|6C9A092F38739A3759793EF8B496569CD02C2E3F|YlbF]-[protein|EBD15C174A03B7FCDFFE4C5DB5D86E93F1B9CAC4|YaaT] complex [Pubmed|29794222]

Biological materials

Mutant

• MGNA-C200 (ydiG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2198 NBRP B. subtilis, Japan]

References

Reviews

• 23539623

Original publications

• 10903949,22383849